Vascular accesses in hemodialysis may present short- and long-term complications, such as hand ischemia. Objective- to evaluate, through infrared thermography, the presence of ischemia in the distal portion of the hands in upper limbs with AVF of patients undergoing RRT. Method: this study had a sample composed of 15 patients undergoing Renal Replacement Therapy (RRT) for hemodialysis through arteriovenous fistula (AVF) who answered a questionnaire prepared by the authors themselves with the following variables: sociodemographic data, diagnosis, signs vitals and AVF data. To obtain the thermograms of the hands, a C5 infrared thermographic camera, FLIR Systems, was used, fixed at 50 cm from the participants' hands, privileging the bilateral framing. For a better understanding of the data, they were organized in an Excel 2011® spreadsheet, later analyzed using the Microcal Origin 6.0 program. Volunteers were divided into two groups: with AVF and without AVF and statistically compared to assess whether there is a difference between means. Results: the sociodemographic variables, of the 15 patients evaluated in this study, the male gender was predominant, age group with an average of 45 years, elementary school (incomplete/completed), married and coming from other cities. Regarding the thermograms, they show significance levels of (P≤0.05), related to the thermal differentiation between the average temperatures of hands with AVF and without AVF with a variation of Δt = 1.78°C. Conclusion: Analysis of changes in blood distribution in both hands has the potential to improve early diagnosis and thus the clinical care of individuals with CKD on RRT. Infrared thermography effectively detected the temperature differences between the hands with and without AVF of patients on RRT, thus being able to provide additional information about the microcirculation of these patients.