The problems of necessity of sustainable and ecological approaches in architectural design of hospitals are raised in the research. The best international experience of designing and operating hospitals designed on the principles of sustainable development is considered. Examples and implementation examples of healthcare institutions integrating energy efficient technologies are analyzed and illustrated: natural ventilation, solar panels, rainwater collection, filtration and reuse of wastewater, greening of the roof and walls, sun protection, aerodynamic volumetric and spatial form. Studying and using the proven experience of the best examples of ecological hospital buildings, recognized and certified at the highest levels of the world institutions for the development of a sustainable future, will allow Ukraine to create the conditions for solving the crisis both in the sphere of health care and in the ecologically preserved environment of the country.